Recombinant Human CCL22 / MDC Protein (His tag) 50µg
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Catalog number
PKSH031817-50µg
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Price
Please ask
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Size
50µg
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Synonym
A-152E5.1;ABCD-1;DC/B-CK;MDC;SCYA22;STCP-1
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Activity
NA
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Sequence
Gly 25-Gln 93
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Fusion tag
N-His
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Accession
O00626
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Expressed Host
E. coli
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
＞90 % as determined by SDS-PAGE
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Endotoxin
Please contact us for more information.
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
9.7 kDa
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AP Mol Mass
10 kDa
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Formulation
Lyophilized from sterile 30% Acetonitrile, 0.1% TFA
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Reconstitution
Please refer to it for detailed information.
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Background
Chemokine (C-C motif) ligand 22(ABCD-1 / CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1 / CCL22 chemokine binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated / effector T lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. ABCD-1 / CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus, and in Langerhans' cell histiocytosis and atopic dermatitis but not in dermatopathic lymphadenopathy. This chemokine is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. This protein is lower expressed in lung and spleen and very weekly expressed in small intestine.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
ADAM11, CCL22, ADAM28, TNFAIP8
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Short name
Recombinant CCL22 / MDC Protein (His tag) 50µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens chemokine (C-C motif) ligand 22 / MDC Protein (histidine detection labelled) 50µg
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Alternative technique
rec
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Alternative to gene target
chemokine (C-C motif) ligand 22, ABCD-1 and DC/B-CK and MDC and SCYA22 and STCP-1, CCL22 and IDBG-33170 and ENSG00000102962 and 6367, chemokine activity, Extracellular, Ccl22 and IDBG-182591 and ENSMUSG00000031779 and 20299, CCL22 and IDBG-632465 and ENSBTAG00000017718 and 616996
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Gene info
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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