BAY-876

Alternative_name

N4-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-Quinolinedicarboxamide
Description

BAY-876 is a highly selective GLUT1 inhibitor (IC₅₀ = 2 mM). Displays good metabolic stability in vitro and high oral bioavailability in vivo.
CAS Number

1799753-84-6
Structure Available

Yes
Molecular Formula

C₂₄H₁₆F₄N₆O₂
Molecular Weight

496.42
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

A highly selective GLUT1 inhibitor
Storage Condition

-20°C
Shipping Condition

Gel Pack
Shelf Life

36 months
PubChem CID

118191391
PubChem CID Link
SMILES

CC1=C(C(=NN1CC2=CC=C(C=C2)C#N)C(F)(F)F)NC(=O)C3=CC(=NC4=C3C=CC(=C4)F)C(=O)N
InChi

InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26,27)28)33-34(12)11-14-4-2-13(10-29)3-5-14)32-23(36)17-9-19(22(30)35)31-18-8-15(25)6-7-16(17)18/h2-9H,11H2,1H3,(H2,30,35)(H,32,36)
InChi Key

BKLJDIJJOOQUFG-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes