CD3Z, NT (CD247, CD3Z, T3Z, TCRZ, T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain, CD247)[CD3Z]

• Catalog number
  MBS641854
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  CD3Z   CD247   CD3Z   T3Z   TCRZ   surface   glycoprotein   CD3   zeta   chain   receptor   zeta   chain   CD247   [CD3Z]  
• Gene symbol
  CD247
• Short name
  CD3Z, NT (CD247, CD3Z, T3Z, TCRZ, T- surface glycoprotein CD3 zeta chain, T- receptor T3 zeta chain, CD247)[CD3Z]
• Host
  Rabbit
• Alternative name
  CD3Z, NT (CD247 molecule, CD3Z, T3Z, TCRZ, T-cellular surface glycoprotein CD3 zeta epitope, T-cellular receptor T3 zeta epitope, CD247 molecule)[CD3Z]
• Alternative to gene target
  CD247 molecule, CD3-ZETA and CD3H and CD3Q and CD3Z and IMD25 and T3Z and TCRZ, CD247 and IDBG-104547 and ENSG00000198821 and 919, protein homodimerization activity, Plasma membranes, Cd247 and IDBG-202777 and ENSMUSG00000005763 and 12503, CD247 and IDBG-629556 and ENSBTAG00000012700 and 281056
• Tissue
  cell

Gene info

• Identity
  HGNC:1677
• Gene
  CD247
• Long gene name
  CD247 molecule
• Synonyms gene
  • CD3Z
• Synonyms gene name
  • CD3z antigen, zeta polypeptide (TiT3 complex)
  • CD247 antigen
• Synonyms
  • CD3H
  • CD3Q
• Synonyms name
  • T-cell surface glycoprotein CD3 zeta chain
• GenBank acession
  • BC025703
• Locus
  1q24.2
• Discovery year
  1989-04-06
• Entrez gene record
  919
• Pubmed identfication
  • 2974162
• RefSeq identity
  • NM_198053
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000034593
• Locus Specific Databases
  • CD247base: Mutation registry for Autosomal recessive CD3Zeta deficiency
  • LRG_36

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