Hepcidin 25 (Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial Peptide)

• Catalog number
  MBS610041
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [Hepcidin 25]
• Products_name_syn
  [Anti -Hepcidin 25 (Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial Peptide)]
• Other_names
  [hepcidin preproprotein; Hepcidin; hepcidin; putative liver tumor regressor; liver-expressed antimicrobial peptide 1; hepcidin antimicrobial peptide; Liver-expressed antimicrobial peptide 1; LEAP-1; Putative liver tumor regressor]
• Other_gene_names
  [HAMP; HAMP; HEPC; PLTR; HFE2B; LEAP1; HEPC; LEAP1; LEAP-1; PLTR; Hepc25; Hepc20]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse
• Specificity
  Recognizes Hepcidin 25. The mouse sequences from mouse/rat and human differ by just 1aa in 25aa mature HEPC. The sequence is truncated by 5aa in the 20aa major secreted HEPC. No significant crossreactivity with 20aa HEPC peptide. May crossreacts with the unprocessed larger 60aa pro-HEPC if present in the samples or tissues.
• Purity
  Serum Serum
• Form
  Supplied as a liquid in 0.05% sodium azide, 40% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.

• Gene target
  Hepcidin   Hepc   LEAP   Hepatic   Bactericidal   Protein   Liver   Expressed   Antimicrobial   Peptide  
• Gene symbol
  LEAP2, HAMP
• Short name
  Hepcidin 25 (Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial Peptide)
• Technique
  peptide, peptides
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Hepcidin 25 (Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial short protein sequence)
• Alternative technique
  peptides
• Tissue
  liver

Gene info

• Identity
  HGNC:29571
• Gene
  LEAP2
• Long gene name
  liver enriched antimicrobial peptide 2
• Synonyms gene name
  • liver expressed antimicrobial peptide 2
• Synonyms
  • LEAP-2
• GenBank acession
  • AJ409065
  • BX443829
• Locus
  5q31.1
• Discovery year
  2006-08-22
• Entrez gene record
  116842
• Pubmed identfication
  • 12493837
• RefSeq identity
  • NM_052971
• VEGA ID
  OTTHUMG00000059837

Gene info

• Identity
  HGNC:15598
• Gene
  HAMP
• Long gene name
  hepcidin antimicrobial peptide
• Synonyms
  • LEAP-1
  • HEPC
  • HFE2B
  • LEAP1
• GenBank acession
  • AF309489
• Locus
  19q13.12
• Discovery year
  2001-05-29
• Entrez gene record
  57817
• Pubmed identfication
  • 11034317
  • 11113132
• RefSeq identity
  • NM_021175
• VEGA ID
  OTTHUMG00000183295
• Locus Specific Databases
  • LRG_791

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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