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Rabbit Anti Human MAP3K8 Polyclonal

Rabbit Anti Human MAP3K8 Polyclonal is available 13 times from Stressmark antibodies labs

SPC-953D-ALP | Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: Alkaline Phosphatase size: 100 µl | 433.07 USD

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SPC-953D-A390 | Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: ATTO 390 size: 100 µl | 440.82 USD

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SPC-953D-A594 | Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: ATTO 594 size: 100 µl | 439.72 USD

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SPC-953D-A680 | Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: ATTO 680 size: 100 µl | 439.72 USD

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SPC-953D-A700 | Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: ATTO 700 size: 100 µl | 439.72 USD

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SPC-953D-P594 | Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: PE/ATTO 594 size: 100 µl | 447.47 USD

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SPC-953D-RPE | Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: RPE size: 100 µl | 436.39 USD

Immunogen A phospho-specific peptide corresponding to residues surrounding Ser334 of human COT (AA331-337)
Antibody's target Human MAP3K8 (pSer334)
Antibody's full description Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal
Certificate of analysis A 1:250 dilution of SPC-953 was sufficient for detection of MAP3K8 (pSer334) in 10 µg of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Test StressMark antibodies supplies antibodies that are for research of human proteins.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name Oryctolagus cuniculus
Gene targetMAP3K8 pSer334 RPE
Short name Rabbit Anti- MAP3K8 (pSer334) Polyclonal: RPE
Label rpe
Alternative name production species: rabbit antibody to-H. sapiens MAP3K8 (pSer334) polyclonal: RPE
MeSH Data
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Product images
    #Human#.jpg

SPC-1117D-ALP | Rabbit Anti-Human MAP3K8 Polyclonal: Alkaline Phosphatase size: 100 µl | 433.07 USD

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SPC-1117D-A488 | Rabbit Anti-Human MAP3K8 Polyclonal: ATTO 488 size: 100 µl | 439.72 USD

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SPC-1117D-A680 | Rabbit Anti-Human MAP3K8 Polyclonal: ATTO 680 size: 100 µl | 439.72 USD

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SPC-1117D-A700 | Rabbit Anti-Human MAP3K8 Polyclonal: ATTO 700 size: 100 µl | 439.72 USD

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SPC-1117D-RPE | Rabbit Anti-Human MAP3K8 Polyclonal: RPE size: 100 µl | 436.39 USD

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SPC-1117D | Rabbit Anti-Human MAP3K8 Polyclonal: Unconjugated size: 100 µl | 386.55 USD

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PubMed number Refer to PubMed
Net weight (g) 0.1
Recommended buffer for storage PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Antibody's reactivity Human
Warning information Non-hazardous
Raised in Rabbit
NCBI number NP_005195
Gene number 1326
Released date 29/Aug/2016
Antibody's other name Cancer Osaka thyroid oncogene Antibody, CCOT Antibody, COT Antibody, EST Antibody, Ewing sarcoma transformant Antibody, M3K8_HUMAN Antibody, MEKK8 Antibody, Mitogen activated protein kinase kinase kinase 8 Antibody, Serine/threonine protein kinase cot Antibody, TPL 2 Antibody, Tumor progression locus 2 Antibody
Protein number P41279
Antibody's recommended dilutions for use WB (1:250); optimal dilutions for assays should be determined by the user.
Tested applications To be tested
Antibody's datasheet Contact our support service to receive datasheet or other technical documentation.
Total weight (kg) 1.4
Stock availabilit In Stock
Scientific context MAP3K8 is a protein serine/threonine kinase that can activate both MAPK and JNKK pathways. It is required for TLR4 activation of the MEK/ERK pathway. It can activate NF-kB1 by stimulating the proteolysis of its inhibitor, p105, and promote the production of TNF-alpha and IL-2 during T-cell activation. It has been shown to mediate Raf-inhibiting drug resistance in BRAF(V600E) cell lines. MAP3K8 may also play a role in the cell cycle.
Tissue specificity Expressed in several normal tissues and human tumor-derived cell lines.
Country of production Canada
Antibody's purified from Peptide Affinity Purified
Antibody's concentration See included datasheet or contact our support service
Tested reactivity To be tested
Antibody in cell Cytoplasm
Antibody's category Polyclonal Antibodies
Representative figure link No Data Available
Bibliography Refer to PubMed
Verified applications WB, AM
Antibody's specificity Detects 52.898 kDa.
Storage recommendations -20°C
Shipping recommendations Blue Ice or 4°C
Technique anti-Human, Polyclonal, Rabbit, anti
Host Rabbit
Species Human
Alternative technique polyclonals
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Rabbit Anti-Human MAP3K8 (pSer334) Polyclonal: RPE
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+32-(0)1-658-90-45 [email protected]
  • MAP3K8
  • pSer334
  • Alkaline
  • Phosphatase
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