anti-EGLN3 Antibody

  • Catalog number
    30-813
  • Price
    Please ask
  • Size
    50 ug
  • Gene info
    EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. It hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. EGLN3 functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. EGLN3 promotes cell death through a caspase-dependent mechanism.
  • Gene names
    EGLN3, FLJ21620, HIFPH3, MGC125998, MGC125999, PHD3, HIFP4H3
  • Antibodie s label
    unlabelled serum
  • Purity
    Antibody is purified by peptide affinity chromatography method.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Antigen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EGLN3.
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    EGLN3 antibody can be used for detection of EGLN3 by ELISA at 1:1562500. EGLN3 antibody can be used for detection of EGLN3 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
  • Suspention pH azide
    Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
  • Keep at
    For short periods of storage (days) store at 4 grades C. For longer periods of storage, store EGLN3 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    11545787
  • Ncbi nr
    NP_071356
  • KDa
    27 kDa
  • Vial with antibody
    Lyophilized
  • Quantity per ml
    1 mg/ml
  • NCBI GENE nr
    112399
  • GENE symbol
    EGLN3
  • Antigene name
    egl-9 family hypoxia-inducible factor 3
  • Source
    Homo sapiens
  • Protein nr
    Q9H6Z9
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    EGLN3  
  • Gene symbol
    EGLN3-AS1, EGLN3
  • Short name
    anti-EGLN3 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toEGLN3 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    egl nine homolog 3 (C. elegans), EGLN3 and IDBG-4515 and ENSG00000129521 and 102724945,112399, oxidoreductase activity, nuclei, Egln3 and IDBG-139438 and ENSMUSG00000035105 and 112407, EGLN3 and IDBG-632414 and ENSBTAG00000008172 and 535578
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
Filters
Contact
Chat with gentaur.com employee