Piperlongumine

• Catalog number
  1919-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  (E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one; 1-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2(1H)-one; Piplartine
• Description
  A constituent of the pepper Piper longum L. that selectively kills cancer cells but not normal cells. Piperlongumine increases the level of reactive oxygen species (ROS) and apoptotic cell death in both cancer cells and normal cells engineered to have a cancer genotype, irrespective of p53 status, but it has little effect on either rapidly or slowly dividing primary normal cells. Also potently inhibits the growth of spontaneously formed malignant breast tumors and their associated metastases in mice.
• CAS Number
  20069-09-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₁₉NO₅
• Molecular Weight
  317.34
• Cell Permeable
  Yes
• Purity
  ≥97%
• Solubilities
  DMSO (~ 25 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  An anticancer agent
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00075706
• PubChem CID
  637858
• PubChem CID Link
• SMILES
  COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O
• InChi
  InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6-15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+
• InChi Key
  VABYUUZNAVQNPG-BQYQJAHWSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Piperlongumine  
• Short name
  Piperlongumine
• Alternative name
  Piperlongumine

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