Caspase 3 Inhibitor, Cell Culture, 2mM, (DEVD-FMK) (CPP-32, Apoptain, Yama, SCA-1)

• Catalog number
  MBS655319
• Price
  Please ask
• Size
  0,1 mL

• Other size
  please contact us to order other different size
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. For cells, cell lines and tissues in culture till half confluency. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Caspase   Inhibitor   Culture   2mM   DEVD-FMK   CPP-32   Apoptain   Yama   SCA-1  
• Gene symbol
  CPP, LY6E, MILR1, IGKV1D-32, SNORD115-32, PPP1R1B, ATXN1, IGLV3-32, IGHV3-32, IGKV1-32
• Short name
  Caspase 3 Inhibitor, Culture, 2mM, (DEVD-FMK) (CPP-32, Apoptain, Yama, SCA-1)
• Technique
  culture
• Alternative name
  caspase 3 suppressor, cellular Culture, 2mM, (DEVD-FMK) (CPP-32, Apoptain, Yama, SCA-1)
• Tissue
  cell

Gene info

• Identity
  HGNC:2322
• Gene
  CPP
• Long gene name
  ceruloplasmin pseudogene
• Synonyms gene name
  • ceruloplasmin (ferroxidase) pseudogene
• GenBank acession
  • M18058
• Locus
  8q21.3
• Discovery year
  2001-06-22
• Entrez gene record
  340451
• Pubmed identfication
  • 3427102
• RefSeq identity
  • NG_001106

Gene info

• Identity
  HGNC:6727
• Gene
  LY6E
• Long gene name
  lymphocyte antigen 6 family member E
• Synonyms gene name
  • lymphocyte antigen 6 complex, locus E
• Synonyms
  • TSA-1
  • RIG-E
  • SCA-2
• Synonyms name
  • retinoic acid induced gene E
• GenBank acession
  • U42376
• Locus
  8q24.3
• Discovery year
  1998-06-19
• Entrez gene record
  4061
• Pubmed identfication
  • 8757598
  • 8650192
• RefSeq identity
  • NM_001127213
• Classification
  • LY6/PLAUR domain containing
• VEGA ID
  OTTHUMG00000164754

Gene info

• Identity
  HGNC:27570
• Gene
  MILR1
• Long gene name
  mast cell immunoglobulin like receptor 1
• Synonyms gene
  • C17orf60
• Synonyms gene name
  • chromosome 17 open reading frame 60
  • mast cell immunoglobulin-like receptor 1
• Synonyms
  • Allergin-1
  • MCA-32
• Synonyms name
  • allergy inhibitory receptor 1
  • mast cell antigen 32
• GenBank acession
  • BC053534
• Locus
  17q23.3
• Discovery year
  2005-12-16
• Entrez gene record
  284021
• Pubmed identfication
  • 20526344
• RefSeq identity
  • NM_001085423
• Classification
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000185198

Gene info

• Identity
  HGNC:5752
• Gene
  IGKV1D-32
• Long gene name
  immunoglobulin kappa variable 1D-32 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 1D-32
• GenBank acession
  • X71896
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28897
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151614

Gene info

• Identity
  HGNC:33051
• Gene
  SNORD115-32
• Long gene name
  small nucleolar RNA, C/D box 115-32
• Synonyms
  • HBII-52-32
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033806
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003347.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:9287
• Gene
  PPP1R1B
• Long gene name
  protein phosphatase 1 regulatory inhibitor subunit 1B
• Synonyms gene name
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B
• Synonyms
  • DARPP-32
  • FLJ20940
• Synonyms name
  • dopamine and cAMP regulated phosphoprotein
• GenBank acession
  • AI124650
• Locus
  17q12
• Discovery year
  1993-01-22
• Entrez gene record
  84152
• Pubmed identfication
  • 8120638
• RefSeq identity
  • NM_032192
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000133210

Gene info

• Identity
  HGNC:10548
• Gene
  ATXN1
• Long gene name
  ataxin 1
• Synonyms gene
  • SCA1
• Synonyms gene name
  • spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1)
• Synonyms
  • D6S504E
  • ATX1
• GenBank acession
  • X79204
• Locus
  6p22.3
• Discovery year
  1986-01-01
• Entrez gene record
  6310
• Pubmed identfication
  • 1582256
• RefSeq identity
  • NM_000332
• Classification
  • Ataxins
• VEGA ID
  OTTHUMG00000014303
• Locus Specific Databases
  • LRG_863

Gene info

• Identity
  HGNC:5914
• Gene
  IGLV3-32
• Long gene name
  immunoglobulin lambda variable 3-32 (non-functional)
• Synonyms gene name
  • immunoglobulin lambda variable 3-32
• GenBank acession
  • Z73645
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28787
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151166

Gene info

• Identity
  HGNC:5595
• Gene
  IGHV3-32
• Long gene name
  immunoglobulin heavy variable 3-32 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 3-32
  • immunoglobulin heavy variable 3-32 pseudogene
• GenBank acession
  • M99664
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28435
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152063

Gene info

• Identity
  HGNC:5736
• Gene
  IGKV1-32
• Long gene name
  immunoglobulin kappa variable 1-32 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 1-32
  • immunoglobulin kappa variable 1-32 pseudogene
• GenBank acession
  • X71883
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28934
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151687

MeSH Data

• Name
  Culture Techniques
• Concept
  Scope note: Methods of maintaining or growing biological materials in controlled laboratory conditions. These include the cultures of CELLS; TISSUES; organs; or embryo in vitro. Both animal and plant tissues may be cultured by a variety of methods. Cultures may derive from normal or abnormal tissues, and consist of a single cell type or mixed cell types.
• Tree numbers
  • E05.481.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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