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Erastin for cell activation

Erastin for cell activation is available 2 times from Biovision labs

2231-1 | Erastin for cell activation size: 1 mg | 195.18 USD


2231-5 | Erastin for cell activation size: 5 mg | 583.15 USD

Catalog number 2231-5
Supplier Biovision
Price 583.15 USD
Size 5 mg
Product images
Description Erastin is a selective antitumor agent that displays greater lethality in human tumour cells harbouring mutations in the oncogenes HRAS, KRAS or BRAF. It binds to mitochondrial volatage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating. Erastin rapidly induces an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling.
Peptide sequence N/A
CAS number 571203-78-6
Molecular weight 547.04
Category Biochemicals
Other name 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone
Molecular formula C₃₀H₃₁ClN₄O₄
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO (>50 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 24 months
Storage instructions Protect from light and moisture
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetErastin for activation
Short name Erastin for activation
Technique activation
Alternative name Erastin to measure cellular activation
Tissue cell
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Erastin for activation | Technique alternative | 01012198126
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • Erastin
  • for
  • activation
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