Anti-TBL1 (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-4219R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  TBL1
• Specificity
  100% sequence similarity with TBL1YTBL1
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  Nucleus
• Antigen Source
  KLH conjugated synthetic peptide derived from human TBL1X
• Gene ID
  6907, 90665
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  TBL1; EBI; F box like/WD repeat protein TBL1X; SMAP 55; SMAP55; TBL 1; TBL1X; Transducin beta like 1; Transducin beta like 1 X linked; Transducin beta like 1 X linked; Transducin beta like 1X; Transducin beta like 1X protein; TBL1X_HUMAN; F-box-like/WD repeat-containing protein TBL1X; Full=Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked..
• Also known as
  TBL1 Polyclonal Antibody
• Other name
  Anti-TBL1 Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  TBL1  
• Gene symbol
  TBL1Y, TBL1X
• Short name
  Anti-TBL1
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  TBL1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:18502
• Gene
  TBL1Y
• Long gene name
  transducin beta like 1 Y-linked
• Synonyms gene name
  • transducin (beta)-like 1, Y-linked
• Synonyms
  • TBL1
• GenBank acession
  • AF332220
• Locus
  Yp11.2
• Discovery year
  2002-05-22
• Entrez gene record
  90665
• RefSeq identity
  • NM_033284
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000035299

Gene info

• Identity
  HGNC:11585
• Gene
  TBL1X
• Long gene name
  transducin beta like 1 X-linked
• Synonyms gene
  • TBL1
• Synonyms gene name
  • transducin (beta)-like 1
  • transducin (beta)-like 1X-linked
• Synonyms
  • EBI
• GenBank acession
  • Y12781
• Locus
  Xp22.31-p22.2
• Discovery year
  1997-06-09
• Entrez gene record
  6907
• Pubmed identfication
  • 10330347
• RefSeq identity
  • NM_005647
• Classification
  • WD repeat domain containing
  • NCoR/SMRT transcriptional repression complex subunits
• VEGA ID
  OTTHUMG00000021117

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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