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Rabbit Polyclonal Ig Anti

Rabbit Polyclonal Ig Anti is available 10 times from Bio logo labs

GRP001 | Rabbit Polyclonal Ig Anti-Bombesin, Gastrin Releasing Peptide size: 0.25 ml | 584.47 USD

Immunogen Synthetic Bombesin (frog) conjugated with bovine thyroglobulin
Specificity Bombesin (pGlu-Gln-Arg-Leu-Gly Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2) and related peptides e.g. Gastrin Releasing Peptide (mammalian homolog aa sequence bold)
Species reactivity Amphibians, Mammalians
Product presentation Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 100 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. Gentaur Art .No. PU002.
Product is supplied as liquid concentrate
Recommended concentration for use 1:50
Protein concentration N/A
Positive control Amphibian brain, gut (peripheral nerves) fetal lung
Pretreatment No protease pre-treatment required. Improvement may be achieved by HIER.
Tested applications IHC(C, P)
Recommended secondary reagent We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005), if higher sensitivity is required VECTASTAIN Elite ABC (Art. No. PK-6101) or ABC AP (Art. No. AK-5001) systems are applicable.
UniProt number Go to UniProt/SwissProt
Litterature 1. Costa M., Furness J.B., Yanaihara N., Yanaihara C., and Moody T.W. (1984) Cell and Tissue res. 235; 285-293 2. Gomi T., Kikuchi Y., Adriensen D., Timmermans J.-P., De Groodt-Lassel M.H.A. et al. (1994) Immunocytochemical survey of the neuroepithelial endocrine system in the respiratory tract of the Tokyo salamander, Hynobis nebulosus tokyoensis TAGO. Histochemistry 102; 425-431.
Tips *Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by bio logo. Rabbit antibodies are very stable and can be stored for several days at room temperature. bio logo adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name Oryctolagus cuniculus
Short name Rabbit Polyclonal Ig Anti-Bombesin, Gastrin Releasing Peptide
Technique Polyclonal, peptide, Rabbit, anti
Alternative name production species: rabbit polyclonal Ig antibody to-Bombesin, Gastrin Releasing short protein sequence
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedObservational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
These findings highlight the role of GRPR signaling in sepsis outcome.
In MDA-MB-231 breast cancer cells, GRP-R and EGF-R synergize to regulate cell migration and IL-8 expression, but not cell proliferation.
Observational study of gene-disease association. (HuGE Navigator)
Our results suggest that, similar to what happens in neutrophils, gastrin-releasing peptide is a migratory, rather than a proliferative, stimulus, for non-small cell lung carcinoma cells, indicating a putative role for gastrin-releasing peptide and gastrin-releasing peptide receptor in metastasis
The expression of GRP-R in uterine tissue during specific phases of the cycle suggests a timely precise physiological action of GRP in these targets; in certain uterine neoplasms, the GRP-R overexpression may contribute to tumor development
The large amounts of GRP-receptors in ovarian tumor vessels suggest a role in tumoral vasculature and possibly angiogenesis.
These findings demonstrate that GRP and GRP-R have important oncogenic properties beyond their established mitogenic functions.
This study is the first to confirm the presence of gastrin-releasing peptide receptor in human glioma specimens and normal human neurons.
Bronchial gastrin-releasing peptide receptor expression was significantly associated with lung cancer in a multivariable logistic regression model adjusted for age, sex, smoking status and pulmonary function. Lung cancer risk was not modified by sex.

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PAX005-0.5 | Rabbit Polyclonal Ig Anti-PAX-5 size: 0.5 ml | 328.98 USD

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SE100 | Rabbit Polyclonal Ig Anti-Serotonin (5-HT) size: 1 ml | 348.19 USD

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SO100 | Rabbit Polyclonal Ig Anti-Somatostatin, SRIF size: 1 ml | 322.19 USD

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TSH001-0.1 | Rabbit Polyclonal Ig Anti-TSH, human Thyroid Stimulating Hormone size: 0.1 ml | 506.46 USD

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Availability Please contact us to check the availability
Antibody's raised in Rabbit
Storage method Store at 2-8°C
Antibody's clone polyclonal
Product category Primary Antibody
Antibody's isotype Ig
Host Rabbit
Alternative technique polyclonals
Tissue thyroid
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