Muristerone A

Alternative_name

2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one
Description

A potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to Ponasterone A (Cat. No. 2183). Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Induces expression of β-galactosidase. Induces apoptosis in cells transfected with wild-type Bax. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.
CAS Number

38778-30-2
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₇H₄₄O₈
Molecular Weight

496.63
Cell Permeable

Yes
Purity

≥95% by HPLC
Solubilities

DMSO or EtOH
Handling

Protect from air and light
Tag Line

An Ecdysone receptor (EcR) agonist
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

24months
MDL Number

MFCD00056450
PubChem CID

122217
PubChem CID Link
SMILES

CC(C)CCC(C(C)(C1CCC2(C1(CC(C3C2=CC(=O)C4(C3(CC(C(C4)O)O)C)O)O)C)O)O)O
InChi

InChI=1S/C27H44O8/c1-14(2)6-7-20(31)25(5,33)19-8-9-26(34)15-10-21(32)27(35)13-17(29)16(28)11-24(27,4)22(15)18(30)12-23(19,26)3/h10,14,16-20,22,28-31,33-35H,6-9,11-13H2,1-5H3/t16-,17+,18+,19-,20+,22+,23+,24+,25+,26+,27+/m0/s1
InChi Key

LRJUYAVTHIEHAI-LHBNDURVSA-N
Data Sheet Link
MSDS Available

Yes