anti-p95 / NBS1 (phospho Ser343) Antibody

• Catalog number
  79-440
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
• Gene names
  ATV, NBS, P95, NBS1, AT-V1, AT-V2, TCF5, PP9092,
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of p95/NBS1 only when phosphorylated at serine 343.
• Antigen
  p95/NBS1 (Phospho-Ser343) antibody was made against a peptide sequence around phosphorylation site of serine 343 (S-L-S (p) -Q-G) derived from Human p95/NBS1.
• Immuno application
  Western Blot
• Antibody advice
  Western Blot: 1:500~1:1000
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  33356172
• Ncbi nr
  NP_002476.2
• KDa
  95 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  4683
• GENE symbol
  NBN
• Antigene name
  nibrin
• Source
  Homo sapiens
• Protein nr
  O60934
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p95   NBS1   phospho   Ser343  
• Gene symbol
  NLRP2, NBN
• Short name
  anti-p95 / NBS1 (phospho Ser343) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody top95 / NBS1 (phosphorilated Ser343) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:22948
• Gene
  NLRP2
• Long gene name
  NLR family pyrin domain containing 2
• Synonyms gene
  • NALP2
• Synonyms gene name
  • NACHT, leucine rich repeat and PYD containing 2
• Synonyms
  • FLJ20510
  • PYPAF2
  • NBS1
  • PAN1
  • CLR19.9
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2
• GenBank acession
  • AK000517
• Locus
  19q13.42
• Discovery year
  2003-10-28
• Entrez gene record
  55655
• Pubmed identfication
  • 12563287
  • 11270363
• RefSeq identity
  • NM_017852
• Classification
  • Pyrin domain containing
  • NLR family
• VEGA ID
  OTTHUMG00000167763

Gene info

• Identity
  HGNC:7652
• Gene
  NBN
• Long gene name
  nibrin
• Synonyms gene
  • NBS
  • NBS1
• Synonyms gene name
  • Nijmegen breakage syndrome 1 (nibrin)
• Synonyms
  • ATV
  • AT-V2
  • AT-V1
• GenBank acession
  • AF058696
• Locus
  8q21.3
• Discovery year
  1997-11-28
• Entrez gene record
  4683
• Pubmed identfication
  • 9590181
  • 9590180
• RefSeq identity
  • NM_001024688
• Classification
  • MRN complex
  • BRCA1 C complex
• VEGA ID
  OTTHUMG00000153546
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_158

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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