PB-SV40-Neo-EF1-GFP-CAGs-cMyc-Klf4-Oct4-Sox2 Mouse 4-in-1 iPSC Vector
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Catalog number
PB400A-1
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Price
Please ask
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Size
10 ug
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Shipping Temperature
Blue Ice/ Dry Ice
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Product category
PiggyBac Technology
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Gene
The c-MYC or myelocytomatosis gene is a transcription factor that is found in cancer and many anti-c-MYC antibodies are used for its detection.
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Description
Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells. The iPSC technology was pioneered by Shinya Yamanaka’s lab in Kyoto, Japan, who showed in 2006 that the introduction of four specific genes encoding transcription factors could convert adult cells into pluripotent stem cells.[1] He was awarded the 2012 Nobel Prize along with Sir John Gurdon "for the discovery that mature cells can be reprogrammed to become pluripotent
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Short name
PB-SV40-Neo-EF1-GFP-CAGs-cMyc-Klf4-Oct4-Sox2 Mouse 4-in-1 iPSC Vector
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Technique
Mouse, ipsc, ipscs are induced pluripotent stem cells by yamanaka or thomson factors. They can be direived from fibroblasts, adipocytes but all other cell types too. mouses, Vectors
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Host
mouse
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Label
gfp
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Species
Mouse, Mouses
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Alternative name
PB-SV40-Neo-EF1-Green Fluorescent-CAGs-cMyc-Klf4-Oct4-SRY (sex determining region Y)-box 2 Mouse 4-in-1 iPSC integrating Desoxyribonucleic acid sequence
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Alternative technique
murine, stemcells
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Alternative to gene target
SRY (sex determining region Y)-box 2, ANOP3 and MCOPS3, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, protein heterodimerization activity, nuclei, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383
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MeSH Data
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Name
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Concept
Scope note:
Procedures used for the induction of CELLULAR REPROGRAMMING to change the terminal phenotype of a cell, such as the generation of INDUCED PLURIPOTENT STEM CELLS from differentiated adult cells by the forced expression of specific genes.
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Tree numbers
- E05.200.500.380
- E05.242.378
- E05.393.085
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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