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anti-D4-GDI Antibody

anti-D4-GDI Antibody is available 1 time from Biovision labs

3385-100 | anti-D4-GDI Antibody size: D4-GDI Antibody | 402.25 USD

Catalog number 3385-100
Supplier Biovision
Price 402.25 USD
Size D4-GDI Antibody
1. Gene info
Identity 17427
Gene DPF3
Long gene name double PHD fingers 3
Synonyms gene name
  • D4, zinc and double PHD fingers, family 3
Synonyms
  • cer-d4
  • Cerd4
  • FLJ14079
  • BAF45c
GenBank acession
  • U43919
Locus 14q24.2
Discovery year 2003-01-28
Entrez gene record 8110
Pubmed identfication
  • 11845289
  • 8812431
Classification
  • PHD finger proteins
  • BAF complex
Havana BLAST/BLAT OTTHUMG00000171364
Product images
    #0#.jpegD4-GDI Antibody
Target of this antibody: D4-GDI
Alternative names of antibody target: ARHGDIB , 602843 , P52566 , D4 , GDIA2 , GDID4 , LYGDI , Ly-GDI , RAP1GN1
Background information: D4-GDI (GDP dissociation inhibitor) is a negative regulator of the ras-related Rho family of GTPases. Since the Rho GTPases promote cytoskeleytal and membrane changes associated with apoptotic cell death, the removal of the D4-GDI block throμgh its cleavage is important for inducing apoptosis. Caspase-3 cleaves the 28kD mature form of D4-GDI to give a 23kDa and 5kDa size fragment. The 23kDa fragment then translocates to the nucleus. The mechanisms involving cleavage of D4-GDI with apoptosis are not presently known. Activation of the Jun N-terminal kinase, a regulator of apoptosis, may be one of the mechanisms.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human
Immunogene sequence: Synthetic peptide near the N-terminus of human D4-GDI
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 28 kDa D4-GDI in human samples. Jurkat cell lysate can be used as a positive control.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetD4-GDI
Short name anti-D4-GDI Antibody
Technique Antibody, anti
Alternative name antibody to-D4-GDI (Antibody to)
Alternative technique antibodies
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anti-D4-GDI Antibody | Technique alternative | 01012192231
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  • D4-GDI
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