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ATP6AP2 Polyclonal Antibody

ATP6AP2 Polyclonal Antibody is available 2 times from Bioma labs

CAC07412 | ATP6AP2 Polyclonal Antibody size: 100 μg | 460.91 USD

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CAC07412 | ATP6AP2 Polyclonal Antibody size: 50 μg | 281.6 USD

Catalog number CAC07412
Supplier bioma
Price281.6 USD
Size 50 μg
1. Gene info
Identity18305
Long gene name ATPase H+ transporting accessory protein 2
Synonyms gene
Synonyms gene name
  • ATPase, H+ transporting, lysosomal interacting protein 2
  • ATPase, H+ transporting, lysosomal accessory protein 2
GenBank acession
LocusXp11.4
Discovery year 2002-05-23
Entrez gene record10159
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000024103
Locus Specific Databases
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedMultiple regression analyses showed a significant association with a large coefficient between the arterial mRNA level of the (pro)renin receptor and the arterial mRNA level of ACE
prospective crucial regions in renin and prorenin responsible for their interaction with the (pro)renin receptor [PRR] were investigated using various kinds of peptides
Studies suggested that the complete deletion of (P)RR was lethal.
Prorenin receptor is mainly localized in the subcellular organelles, such as the endoplasmic reticulum and Golgi apparatus, and the prorenin receptor is cleaved by ADAM19 in the Golgi, resulting in two fragments.
existence of a novel signal transduction pathway involving the ligand renin, renin receptor, and the transcription factor PLZF
evidence for the AngII-independent MAPK activation by human (pro)renin receptor and induction of glomerulosclerosis with increased TGF-beta1 expression
Data indicate that high circulating levels of s(P)RR at early pregnancy predicted a subsequent elevation in blood pressure, and high concentrations at delivery were significantly associated with preeclampsia.
Crosstalk between (Pro)renin receptor and COX-2 in the renal medulla during angiotensin II-induced hypertension
A mutation in the splice site following exon 2 may affect splicing due to its close proximity to the exon-intron boundary. It was associated with epilepsy, Parkinsonism and intellectual disability in 2 brothers.
Study identifies a renin-angiotensin system-independent function for the (P)RR in the regulation of LDL metabolism by controlling the levels of SORT1 and LDL receptor.
Gene ontology - Molecular functionprotein binding
receptor activity
enzyme binding
Other name ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,ER-localized type I transmembrane adaptor,Embryonic liver differentiation factor 10,N14F,Renin/prorenin receptor,Vacuolar ATP synthase membrane sector-associated protein M8-9,HT028, MSTP009, PSEC0072,ATP6IP2, CAPER, ELDF10,ATP6AP2
Clonality Polyclonal
Purity Caprylic Acid Ammonium Sulfate Precipitation Purified
Estimated production time 3-7 business days
Raised in Rabbit
NCBI number Please refer to NCBI
Gene number Please refer to GenBank
Immunogen Recombinant human Renin receptor protein (1-176AA)
Protein number O75787
Notes For research use only. Not for diagnostic procedures.
Use before 1 year
Storage recommendation Aliquot and store at -20°C. Minimize freezing and thawing.
Shipping requirements Blue ice
Verified reactivity Human
Supplementary information Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).
Verified applications ELISA,WB
Properties If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation anticorps
Gene targetATP6AP2
Short name ATP6AP2 Polyclonal Antibody
Technique Polyclonal, Antibody
Alternative name ATP6AP2 polyclonal (Antibody to)
Alternative technique polyclonals
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