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anti-TrkB Antibody

anti-TrkB Antibody is available 1 time from Biovision labs

3593-100 | anti-TrkB Antibody size: TrkB Antibody | 438.48 USD

Catalog number 3593-100
Supplier Biovision
Price 438.48 USD
Size TrkB Antibody
1. Gene info
Identity 8032
Gene NTRK2
Long gene name neurotrophic receptor tyrosine kinase 2
Synonyms gene name
  • neurotrophic tyrosine kinase, receptor, type 2
Synonyms
  • TRKB
Synonyms name
  • BDNF/NT-3 growth factors receptor
GenBank acession
  • AF410902
Locus 9q21.33
Discovery year 1991-07-18
Entrez gene record 4915
Pubmed identfication
  • 7789988
Classification
  • Receptor tyrosine kinases
  • I-set domain containing
Havana BLAST/BLAT OTTHUMG00000020120
Product images
    #0#.jpegTrkB Antibody
Target of this antibody: TrkB
Alternative names of antibody target: NTRK2 , GP145-TrkB , TRKB , Trk-B , tyrosine receptor kinase
Background information: Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting throμgh trkB such as BDNF.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse, rat, chicken
Immunogene sequence: Synthetic peptide surrounding amino acid 810 of human TrkB
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.2 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot, Immunoprecipitation, Immunofluorescence
Recommended usage: Western blotting (0.5-4 µg/ml), immunofluorescence (5-10 µg/ml). However, the optimal concentrations should be determined individually. Trk protein exists as variably glycosylated entities with the major forms having molecular weights of 140 kDa, 110 kDa, and the unglycosylated form of 80 kDa.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetTrkB
Short name anti-TrkB Antibody
Technique Antibody, anti
Alternative name antibody to-TrkB (Antibody to)
Alternative technique antibodies
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anti-TrkB Antibody | Technique alternative | 01012192570
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