Human CellExp™ CLEC3B / Tetranectin, Human recombinant

• Catalog number
  P1058-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  CLEC3B, Tetranectin, TN, TNA
• Alternative_names
  CLEC3B, Tetranectin, TN, TNA
• Description
  Protein that binds to plasminogen and to isolated kringle 4 and involved in the packaging of molecules destined for exocytosis.
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  > 95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Activity Specifications test method
  Measured by its binding ability in a functional ELISA.
• Biological activity
  Measured by its binding ability to bind 50% of immobilized human recomninant HGF in a functional ELISA in a range of approximately 1 - 10 µg/ml.
• Binding Capacity
  Immobilized human recomninant HGF can bind 50% of recombinant human CLEC3B in a range of approximately 1 - 10 µg/ml.
• Molecular Weight
  21 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in 1X PBS to the desired protein concentration.
• Background Information
  C-type lectin domain family 3 member B (CLEC3B) is also known as Tetranectin, Plasminogen kringle 4-binding protein, is a secreted homotrimer. CLEC3B contains 1 C-type lectin domain and mainly found in plasma. Tetranectin / CLEC3B binds to plasminogen and to isolated kringle 4. CLEC3B may be involved in the packaging of molecules destined for exocytosis. Decreased plasma Tetranectin or increased Tetranectin in stroma of cancers correlates with cancer progression and adverse prognosis.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   CLEC3B   Tetranectin  
• Gene symbol
  CLEC3B
• Short name
  CellExp™ CLEC3B / Tetranectin, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ CLEC3B / Tetranectin, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:11891
• Gene
  CLEC3B
• Long gene name
  C-type lectin domain family 3 member B
• Synonyms gene
  • TNA
• Synonyms gene name
  • tetranectin (plasminogen binding protein)
  • C-type lectin domain family 3, member B
• Synonyms
  • TN
• Locus
  3p21.31
• Discovery year
  1993-08-26
• Entrez gene record
  7123
• RefSeq identity
  • NM_003278
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000133087

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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