5-Aza-2'-deoxycytidine
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Catalog number1754-10
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PricePlease ask
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Size10 mg
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Alternative_name4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,5-triazin-2(1H)-one; Decitabine
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DescriptionAn epigenetic modifier. Decitabine is an analogue of the nucleoside 2’-deoxycytidine. It is believed to exert its antineoplastic effects after phosphorylation and direct incorporation into DNA and inhibition of DNA methyltransferase, causing hypomethylation of DNA and cellular differentiation or apoptosis. DNA hypomethylation is achieved at concentrations below those required to significantly inhibit DNA synthesis, which may promote restoration of function to genes associated with control of cellular differentiation and proliferation.
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CAS Number2353-33-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₈H₁₂N₄O₄
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Molecular Weight228.08
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (25 mg/ml), 50% acetic acid (25 mg/ml)
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HandlingProtect from air and moisture
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Tag LineAn epigenetic modifier
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD00043011
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PubChem CID451668
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SMILESC1C(C(OC1N2C=NC(=NC2=O)N)CO)O
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InChiInChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1
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InChi KeyXAUDJQYHKZQPEU-KVQBGUIXSA-N
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MSDS AvailableYes
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Gene target
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Short name5-Aza-2'-deoxycytidine
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Alternative name5-Aza-2'-deoxycytidine
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