PGC-1alpha Antibody

• Catalog number
  3934-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  PGC-1alpha
• Target Alternative Name
  peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PPAR Gamma Coactivator-1, Pgc-1alphaa, PPAR gamma coactivator variant form, PGC-1-alpha, PPARGC-1-alpha, PPAR-gamma coactivator 1-alpha
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 766 of mouse PGC-1alpha
• Accession
  NP_032930.1
• Gene Id
  19017
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit anti-PGC-1alpha polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Jurkat cell lysate
• Application And Usages
  Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control.
• Description
  The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may also be involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PGC-1alpha  
• Gene symbol
  PGC, PPARGC1A
• Short name
  PGC-1alpha Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  PGC-1alpha (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8890
• Gene
  PGC
• Long gene name
  progastricsin
• Synonyms gene name
  • progastricsin (pepsinogen C)
• Synonyms name
  • pepsinogen C
• Locus
  6p21.1
• Discovery year
  2001-06-22
• Entrez gene record
  5225
• Classification
  • Pepsinogens
• VEGA ID
  OTTHUMG00000014683

Gene info

• Identity
  HGNC:9237
• Gene
  PPARGC1A
• Long gene name
  PPARG coactivator 1 alpha
• Synonyms gene
  • PPARGC1
• Synonyms gene name
  • peroxisome proliferative activated receptor, gamma, coactivator 1
  • peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
• Synonyms
  • PGC1
  • PGC1A
  • PGC-1alpha
• Synonyms name
  • PPARgamma coactivator 1alpha
• GenBank acession
  • AF106698
• Locus
  4p15.2
• Discovery year
  1999-08-02
• Entrez gene record
  10891
• Pubmed identfication
  • 10585775
• RefSeq identity
  • NM_013261
• Classification
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000097747

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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