LY-2090314 is a potent and selective ATP-competitive inhibitor of Glycogen synthase kinase-3 (GSK-3) (IC₅₀ = 1.5 NM for GSK-3α and 0.9 nM for GSK-3β). LY-2090314 plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.
Is it cell-permeable?
≥98% by HPLC
Is this a salt?
Protect from air and light
Maximum time for storage
Off-white to light yellow solid
DMSO (~10 mg/ml)
For cells, cell lines and tissues in culture till half confluency.