Recombinant Human Leptin

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene

Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Leptin
Gene symbol

LEP, LEPR, LEPROT
Short name

Recombinant Leptin
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. genDEPOT advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens Leptin
Alternative technique

rec

Identity

HGNC:6553
Gene

LEP
Long gene name

leptin
Synonyms gene
- OBS
- OB
Synonyms gene name
- leptin (murine obesity homolog)
- leptin (obesity homolog, mouse)
Locus

7q32.1
Discovery year

1993-01-26
Entrez gene record

3952
Pubmed identfication
- 1686014
- 16932309
Classification
- Neuropeptides
VEGA ID

OTTHUMG00000157564

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data