IL-16 Recombinant Protein

• Catalog number
  40-597
• Price
  Please ask
• Size
  0.01 mg

• About recombinant protein
  IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues. .
• Other name of the recombinant
  LCF, NIL16, PRIL16, prIL-16, Pro-interleukin-16, Lymphocyte chemoattractant factor, IL-16
• Recombinant in
  E. coli
• His tag on the recombinant protein
  no His tag
• SEQUENCE
  SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S
• Activity
  Determined by its ability to chemoattract human peripheral blood lymphocytes using a concentration range of 50.0-1000.0 ng/mL.
• Keep at
  The lyophilized IL-16 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-16 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-16 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  289063395
• Accession nr
  NP_001165599.1
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  3603
• Gene name
  interleukin 16
• Source
  Homo sapiens
• Uniprot
  Q14005
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-16   Protein  
• Gene symbol
  IL16
• Short name
  IL-16 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Interleukin-16 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:5980
• Gene
  IL16
• Long gene name
  interleukin 16
• Synonyms gene name
  • interleukin 16 (lymphocyte chemoattractant factor)
• Synonyms
  • LCF
  • IL-16
  • prIL-16
  • HsT19289
  • FLJ42735
  • FLJ16806
• Synonyms name
  • prointerleukin 16
  • lymphocyte chemoattractant factor
• GenBank acession
  • U82972
• Locus
  15q25.1
• Discovery year
  1997-07-25
• Entrez gene record
  3603
• Pubmed identfication
  • 9144227
• RefSeq identity
  • NM_172217
• Classification
  • Interleukins
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000144186

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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