Epalrestat

• Catalog number
  2397-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid
• Description
  Epalrestat is an aldose reductase inhibitor (IC₅₀ = 10 nM (rat lens) and 25 nM (human placenta). It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic neuropathy.
• CAS Number
  82159-09-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₁₃NO₃S₂
• Molecular Weight
  319.4
• Cell Permeable
  Yes
• Purity
  ≥98% by TLC
• Solubilities
  DMSO (~5 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  An aldose reductase inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  1549120
• PubChem CID Link
• SMILES
  CC(=CC1=CC=CC=C1)C=C2C(=O)N(C(=S)S2)CC(=O)O
• InChi
  InChI=1S/C15H13NO3S2/c1-10(7-11-5-3-2-4-6-11)8-12-14(19)16(9-13(17)18)15(20)21-12/h2-8H,9H2,1H3,(H,17,18)/b10-7+,12-8-
• InChi Key
  CHNUOJQWGUIOLD-NFZZJPOKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Epalrestat  
• Short name
  Epalrestat
• Alternative name
  Epalrestat

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