anti-AKT2 Antibody

• Catalog number
  48-432
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  AKT2 encodes a RAC/AKT-type protein kinase that contains a N-terminal pleckstrin-homology (PH) domain and a central catalytic domain closely related to both cAMP-dependent protein kinase and protein kinase C. The protein is a member of PI3K-mediated signalling pathways associated with the regulation of proliferation, survival, protein synthesis, and metabolism. It is activated by a variety of growth factors. AKT2 has been shown to be transcriptionally regulated by MyoD and to activate MyoD-myocyte enhancer binding factor-2 (MEF2) transactivation activity during muscle differentiation. Glycogen synthase kinase 3 (GSK-3) also has been shown to be a downstream target of AKT2. The AKT2 gene is one of the human homologues of v-akt, the transduced oncogene of the AKT8 virus, which induces lymphomas in mice. It has been implicated in breast, ovarian, and pancreatic cancers.
• Gene names
  AKT2, PKB beta, PKBBETA, PRKBB, Protein kinase Akt-2, Protein kinase B beta, RAC-PK-beta, Rac protein kinase beta, RAC-BETA, HIHGHH, PKBB
• Antibodie s label
  unlabelled serum
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  AKT2 antibody was made against a peptide corresponding to the C-Terminus of AKT2 (Human).
• Immuno application
  Western Blot, immuno-histo-chemistry, immuno precipitation
• Antibody advice
  AKT2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, and immunofluorescence starting at 1:200 - 1:1000.
• Suspention pH azide
  PBS, 0.05% sodium azide.
• Keep at
  Store AKT2 antibody at 4 grades C, Avoid Freezing
• Works with
  Human, Mouse, Rat
• Omim nr
  1170703
• Ncbi nr
  P31751
• Vial with antibody
  in solution
• NCBI GENE nr
  208
• GENE symbol
  AKT2
• Antigene name
  v-akt murine thymoma viral oncogene homolog 2
• Source
  Homo sapiens
• Protein nr
  P31751
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AKT2  
• Gene symbol
  AKT2
• Short name
  anti-AKT2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toAKT2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  v-akt murine thymoma viral oncogene homolog 2, HIHGHH and PKBB and PKBBETA and PRKBB and RAC-BETA, AKT2 and IDBG-51270 and ENSG00000105221 and 208, transferase activity, nuclei, Akt2 and IDBG-161456 and ENSMUSG00000004056 and 11652, AKT2 and IDBG-637808 and ENSBTAG00000001400 and 534923

Gene info

• Identity
  HGNC:392
• Gene
  AKT2
• Long gene name
  AKT serine/threonine kinase 2
• Synonyms gene name
  • v-akt murine thymoma viral oncogene homolog 2
• Synonyms
  • PKBβ
• GenBank acession
  • M77198
• Locus
  19q13.2
• Discovery year
  1992-11-05
• Entrez gene record
  208
• Pubmed identfication
  • 1409633
• RefSeq identity
  • NM_001626
• Classification
  • AKT kinases
  • Pleckstrin homology domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000137375
• Locus Specific Databases
  • LRG_1391

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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