SFTPD, human recombinant

• Catalog number
  7328-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  Pulmonary surfactant-associated protein D precursor, COLEC7, PSP-D, SFTP4, SP-D
• Alternative_names
  Pulmonary surfactant-associated protein D precursor, COLEC7, PSP-D, SFTP4, SP-D
• Description
  Involved in the development of acute and chronic inflammation of the lung
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥80%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per 1 microgram of protein
• Molecular Weight
  18.9 kDa (175 aa, 224-375 aa + His Tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  1 mg/ml
• Appearance
  Liquid
• Physical form description
  1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 0.4 M Urea.
• Background Information
  SFTPD, as known as Surfactant pulmonary-associated protein D, is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. It is humoral molecules of the innate immune system, and is considered a functional candidate in chronic periodontitis. Besides it is involved in the development of acute and chronic inflammation of the lung. Several human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. Recombinant human SFTPD protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Amino acid sequence
  MGSSHHHHHH SSGLVPRGSH MGSVASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  SFTPD  
• Gene symbol
  SFTPD-AS1, SFTPD
• Short name
  SFTPD, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  surfactant protein D, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  surfactant protein D, COLEC7 and PSP-D and SFTP4 and SP-D, SFTPD and IDBG-80187 and ENSG00000133661 and 6441, carbohydrate binding, Extracellular, Sftpd and IDBG-151871 and ENSMUSG00000021795 and 20390, SFTPD and IDBG-631071 and ENSBTAG00000046421 and 282072

Gene info

• Identity
  HGNC:51589
• Gene
  SFTPD-AS1
• Long gene name
  SFTPD antisense RNA 1
• GenBank acession
  • AK124605
• Locus
  10q22.3
• Discovery year
  2015-03-11
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000186448

Gene info

• Identity
  HGNC:10803
• Gene
  SFTPD
• Long gene name
  surfactant protein D
• Synonyms gene
  • SFTP4
• Synonyms gene name
  • surfactant, pulmonary-associated protein D
• Synonyms
  • SP-D
  • COLEC7
• GenBank acession
  • L05485
• Locus
  10q22.3
• Discovery year
  1992-06-26
• Entrez gene record
  6441
• Pubmed identfication
  • 1898081
  • 1339284
• Classification
  • Collectins
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000018590

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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