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Eotaxin Mouse

Eotaxin Mouse is available 1 time from Genways bulk labs

GWB-9A125F | Eotaxin Mouse size: bulk | 0.00 USD

Catalog number GWB-9A125F
Price0.00 USD
Size bulk
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1. Gene info
Identity10610
GeneCCL11
Long gene name C-C motif chemokine ligand 11
Synonyms gene
Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
  • chemokine (C-C motif) ligand 11
Synonyms name
GenBank acession
Locus17q12
Discovery year 1996-04-24
Entrez gene record6356
Pubmed identfication
RefSeq identity
Classification
  • Chemokine ligands
  • Endogenous ligands
Havana BLAST/BLATOTTHUMG00000132884
Additional information
PubMedThe ability of IL-13 to induce eosinophilic esophagitis was abolished in STAT6-deficient mice, nearly completely ablated in IL-5-deficient mice, and significantly diminished in eotaxin-1-deficient mice.
concentrations of eotaxin in the CSF of Angiostrongylus cantonensis infected mice each week after infection were all significantly higher than those in serum ( P<0.0001).
CCL11 is the salient but not the sole eosinophil chemoattractant of biological significance during gastrointestinal helminth infection.
eosinophils via chemokine (C-C) receptor 3 have a central role in chronic allergic airway disease
There was a higher tumor incidence in CCL11(-/-) BALB/c mice, which was associated with a reduced eosinophil influx into tumors.
Heligmosomoides infection led to reduction in number of lung eosinophils with decreased levels of eotaxin in bronchoalveolar lavage fluid, lowered of CCR3 receptor expression on eosinophils and impaired chemotaxis of these cells toward eotaxin.
TNC expression controls eotaxin level in apo E-/- mice and that this chemokine plays a key role in the development of atherosclerosis
Data indicate that the combination of Ovalbumin (OVA) and hypoxia induced a enhanced expression of HIF-1alpha and increased eotaxin-1, lung TGB-beta1 expression, and indices of airway remodeling.
Protection of montelukast on OVA-induced eosinophilic gastroenteritis via modulating IL-5, eotaxin-1 and MBP expression.
Study demonstrated that CCL11 is primarily produced by activated astrocytes in the CNS, activates microglia to produce ROS via NOX1, and exacerbates excitotoxic neuronal death
Gene ontology - Cellular componentextracellular space
extracellular region
Product images
    #G#.jpg#Mouse#.jpg#.png
Old catalog number 10-663-45015
Category research antibodies, ELISAs, e. Coli rec. human proteins
Store store in freezer for long therm or fridge for short time storage
Available sizes 5ug:83,20ug:182,1000ug:3553
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name Mus musculus
Gene targetEotaxin
Short name Eotaxin Mouse
Technique Mouse
Host mouse
Species Mouse
Alternative name Eotaxin Mouse
Alternative technique murine
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