Active Human Calpain 1

  • Catalog number
    1134-1000
  • Price
    Please ask
  • Size
    1 mg
  • Synonyms
    Calpain
  • Alternative_names
    Calcium-activated neutral proteinase 2, Short name=CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, Short name=M-calpain
  • Description
    A cysteine protease involved in apoptosis activation
  • Recombinant
    No
  • Source
    Human Erythrocyte
  • Purity by SDS PAGE
    ≥95%
  • Assay
    SDS-PAGE
  • Activity Specifications test method
    >1000 units/mg protein
  • Unit Definition
    One unit is defined as the amount of enzyme that will hydrolyze one pmol Suc-LLVY-AMC per minute at 25 °C.
  • Molecular Weight
    112.0 kDa
  • Storage Temp
    -70°C
  • Shipping
    gel pack
  • Shelf Life
    12 months
  • Appearance
    Liquid
  • Physical form description
    In 20 mM imidazole-HCl, 5 mM β-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol, pH 6.8.
  • Background Information
    Ca²ᶧ-dependent cysteine proteinase with low Ca²ᶧrequirement (half maximal activation = 2 µM). Participates in the ATP release reaction of platelets stimulated with thrombin. Involves in apoptosis activation.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Gene target
    Active   Calpain  
  • Short name
    Active Calpain 1
  • Species
    Human, Humans
  • Alternative name
    functionnal H. sapiens Calpain 1
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