Rabbit anti PINK1
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Catalog numberX2764P
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PricePlease ask
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Size100 μg
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CategoryPrimary Antibodies
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Long descriptionProtects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation. Defects in PINK1 are the cause of Parkinson disease type 6 (PARK6). A neurodegenerative disorder characterized by parkinsonian signs such as rigidity, resting tremor and bradykinesia. A subset of patients manifest additional symptoms including hyperreflexia, autonomic instability, dementia and psychiatric disturbances. Symptoms show diurnal fluctuation and can improve after sleep.
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Antibody come fromHybridoma produced from mice immunized with human peripheral blood mononuclear cells.
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Antigen Immunoaffiinity Purification
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ClonePolyclonal
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Antigen antibody binding interactionRabbit anti PINK1 Antibody
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Antibody is raised inRabbit
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWestern blot, Immunohistochemistry, EIA
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Antibody s suited forAntibody can be used for Western blotting (1-10 µg/ml), Immunoprecipitation (1-2 µg per 100-500 µg of total protein), Immunofluorescence (2-20ʵg/ml), Immunohistochemistry (2-20 µg/ml). Optimal concentration should be evaluated by serial dilutions.
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Storage-20ºC
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Relevant referencesAbo, T., et al. J. Immuno., 127, 1024 (1984)
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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AboutRabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolPINK1-AS, PINK1
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Short nameRabbit anti PINK1
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TechniqueRabbit, anti, antibody to
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HostRabbit, Rabbits
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Isotypenot specified
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Labelunlabeled
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Alternative nameproduction species: rabbit antibody to phosphatase and tensin homolog induced putative kinase 1
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Alternative techniquerabbit-anti, antibodies
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Alternative to gene targetPTEN induced putative kinase 1, PINK1 and IDBG-92922 and ENSG00000158828 and 65018, transferase activity, nuclei, Pink1 and IDBG-199773 and ENSMUSG00000028756 and 68943, PINK1 and IDBG-645657 and ENSBTAG00000006084 and 510683
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Gene info
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Identity
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Gene
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Long gene namePINK1 antisense RNA
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Synonyms gene
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Synonyms gene name
- PINK1 antisense RNA 1 (non-protein coding)
- PINK1 antisense RNA (non-protein coding)
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Synonyms
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GenBank acession
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Locus
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Discovery year2010-08-19
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Pubmed identfication
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePTEN induced kinase 1
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Synonyms gene
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Synonyms gene name
- Parkinson disease (autosomal recessive) 6
- PTEN induced putative kinase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data