12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid-d4

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Cas number

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Chemical s molecular weight

324.49
Chemical s main applications

A labelled fatty acid metabolite of arachidonic acid (A765000). Potential biomarker for asthma monitoring and diagnosis. Stimulates protein kinase C-mediated release of cathepsin B from malignant cells. Used in the study of mechanisms controlling cell cycle arrest and induction of apoptosis in prostate cancer cells via 12-lipoxygenase inhibition.
Chemical s category

Aliphatics, Glycerols, Fatty Acid Derivatives & Lipids, Isotope Labelled Compounds, Metabolites & Impurities
Other name

[S-(E,Z,Z,Z)]-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4; 12-HETE-d4; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4; 12-Hydroxyeicosatetraenoic Acid-d4; 12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4;
Chemical s formula

C20H28D4O3
Physical properties

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Melting temperature

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Boiling temperature

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Chemical s soluble in

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Stability conditions

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Storage

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Chemical s specifications