Anti-Apo-1 (Polyclonal), ALEXA Fluor 594
-
Catalog numberGENTObs-6477R-A594
-
PricePlease ask
-
Size100 microliters
-
-
TypeConjugated Primary Antibody
-
Conjugated withALEXA FLUOR® 594
-
Host organismRabbit (Oryctolagus cuniculus)
-
Target Protein PeptideApo-1
-
SpecificityThis antibody reacts specifically with Apo-1
-
ModificationNo modification has been applied to this antibody
-
Modification siteNone
-
ClonalityPolyclonal Antibody
-
ClonePolyclonal Antibodies
-
Concentration1ug per 1ul
-
Subcellular locationsExtracellular
-
Antigen SourceKLH conjugated synthetic peptide derived from human FAS/Apo-1
-
Gene ID355
-
Swiss ProtP25445
-
ApplicationsIF(IHC-P)
-
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
-
Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
-
Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
-
Background informationReceptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
-
Purification methodPurified by Protein A.
-
StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
-
Excitation emission590nm/617nm
-
SynonymsAPT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; FAS
-
Also known asApo-1 Polyclonal Antibody
-
Other nameAnti-Apo-1 Polyclonal
-
AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
PropertiesFor facs or microscopy Alexa 1 conjugate.
-
ConjugationAlexa Fluor, ALEXA FLUOR® 594
-
ConjugatedAlexa conjugate 1
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
Gene target
-
Gene symbolPTPN13, FAS, TNFRSF25
-
Short nameAnti-Apo-1
-
TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 594
-
Alternative nameApo-1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
-
Alternative techniquepolyclonals, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameprotein tyrosine phosphatase non-receptor type 13
-
Synonyms gene name
- protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1995-02-17
-
Pubmed identfication
-
Classification
- Protein tyrosine phosphatases non-receptor type
- PDZ domain containing
- FERM domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameFas cell surface death receptor
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 6
- Fas (TNF receptor superfamily, member 6)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1992-06-25
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tumor necrosis factor receptor superfamily
- Death inducing signaling complex
- CD molecules
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameTNF receptor superfamily member 25
-
Synonyms gene
-
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
- tumor necrosis factor receptor superfamily, member 25
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-12-04
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Tumor necrosis factor receptor superfamily
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data