MyD88 Antibody

  • Catalog number
    3244R-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    MYD88
  • Target Alternative Name
    Myeloid differentiation primary response protein, MyD88
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, mouse, rat, monkey
  • Immunogen Sequence
    Synthetic peptide surrounding amino acid 283 of rat MyD88
  • Accession
    Q6Y1S1
  • Gene Id
    301059
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    100 µg (0.5 mg/ml) affinity purified rabbit anti- MyD88 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal
  • Purification
    Affinity purified
  • Application
    Western blot
  • Positive Control
    Rat kidney tissue lysate
  • Application And Usages
    Western Blot analysis (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3244RBP-50) is available separately.
  • Description
    MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment. Dominant-negative form of MyD88 attenuates IL-1R-mediated NF-B activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in loss of cellular responses to IL-1 and IL-18. MyD88 is a general adaptor protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. MyD88 gene is expressed in many tissues.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    MyD88  
  • Gene symbol
    MYD88, TIRAP, MAL
  • Short name
    MyD88 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    myeloid differentiation primary response 88 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    myeloid differentiation primary response 88, MYD88D, MYD88 and IDBG-25713 and ENSG00000172936 and 4615, TIR domain binding, Plasma membranes, Myd88 and IDBG-204565 and ENSMUSG00000032508 and 17874, MYD88 and IDBG-644299 and ENSBTAG00000000563 and 444881
Gene info
  • Identity
  • Gene
  • Long gene name
    MYD88 innate immune signal transduction adaptor
  • Synonyms gene name
    • myeloid differentiation primary response gene (88)
    • myeloid differentiation primary response 88
  • GenBank acession
  • Locus
  • Discovery year
    1997-12-23
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • TIR domain containing
    • My-T-BRC complex
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee