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Lenvatinib for cell activation

Lenvatinib for cell activation is available 2 times from Biovision labs

B1157-5 | Lenvatinib for cell activation size: 5 mg | 161.11 USD

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B1157-25 | Lenvatinib for cell activation size: 25 mg | 469.72 USD

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Other name 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide; E7080
Supplied with N/A
Description Lenvatinib is a potent inhibitor of multiple receptor tyrosine kinases, with IC₅₀ values of  22 nM, 4 nM, 5.2 nM, 39 nM and 35 nM on VEGFR-1, VEGFR-2, VEGFR-3, PDGFRβ and RET, respectively. It inhibits SCF- and VEGF-induced angiogenesis of human umbilical vein endothelial cells that express the SCF receptor KIT, with IC₅₀ values of 5.2 nM and 5.1 nM, respectively. Lenvatinib inhibits tumor growth in the human small cell lung cancer H146 xenograft model.
Category Biochemicals
Molecular formula C₂₁H₁₉ClN₄O₄
Is it cell-permeable? Yes
Molecular weight 426.85
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 417716-92-8
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Crystalline solid
Reconstitute instructions DMSO (>35 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name Lenvatinib for activation
Technique activation
Alternative name Lenvatinib to measure cellular activation
Tissue cell
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