AKR1A1 Antibody (CT)

• Catalog number
  6738-100
• Price
  Please ask
• Size
  100 μl

• Antibody Target
  AKR1A1
• Target Alternative Name
  AKR1A1; ALDR1; ALR; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human. Predicted cross reactivity with Mouse, Rat, Bovine and Pig samples.
• Immunogen Sequence
  This AKR1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-325 amino acids from the C-terminal region of human AKR1A1.
• Accession
  P14550
• Gene Id
  10327
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl of antibody in PBS with 0.09% (W/V) sodium azide
• Purification
  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Application
  Western blot, IHC
• Positive Control
  Western blot: Y79, 293 cell line lysates, IHC: human hepatocarcinoma
• Application And Usages
  Western blot: ~1:1000, IHC: ~1:10 – 1:50
• Description
  AKR1A1 (aldo-keto reductase family 1 member A1), also known as ALR (aldehyde reductase), DD3 (dihydrodiol dehydrogenase 3) or ALDR1 (alcohol dehydrogenase), is a widely and abundantly expressed member of the aldo-keto reductase (AKR) family of proteins. Members of the AKR family are soluble NADPH-dependent oxidoreductases. They play important roles in the metabolism of drugs, carcinogens and reactive aldehydes. AKR1A1 exists as a monomer and catalyzes the reduction of xenobiotic and biogenic aldehydes and ketones to their corresponding alcohols. In particular, AKR1A1 efficiently catalyzes medium-chain and aromatic aldehydes. AKR1A1 participates in the biosynthetic pathways of cholesterol and triglyceride and plays a role in the activation of polycyclic aromatic hydrocarbons (PAHs).
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AKR1A1  
• Gene symbol
  AKR1A1
• Short name
  AKR1A1 Antibody (CT)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  AKR1A1 (antibody to-) (CT)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:380
• Gene
  AKR1A1
• Long gene name
  aldo-keto reductase family 1 member A1
• Synonyms gene name
  • aldo-keto reductase family 1, member A1 (aldehyde reductase)
• Synonyms
  • ALR
  • DD3
• Synonyms name
  • dihydrodiol dehydrogenase 3
  • aldehyde reductase
• GenBank acession
  • J04794
• Locus
  1p34.1
• Discovery year
  1998-09-29
• Entrez gene record
  10327
• Pubmed identfication
  • 2498333
  • 10393438
• RefSeq identity
  • NM_006066
• Classification
  • Aldo-keto reductases
• VEGA ID
  OTTHUMG00000007740

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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