anti-TRAF2 Antibody
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Catalog number3661
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoTRAF2 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a TNF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-kB activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.
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Gene namesTRAF2 Antibody: TRAP, TRAP3, MGC:45012, TNF receptor-associated factor 2, E3 ubiquitin-protein ligase TRAF2
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Antibodie s labelunlabelled serum
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PurityTRAF2 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenTRAF2 antibody was made against a 17 amino acid synthetic peptide from near the carboxy terminus of human TRAF2.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno precipitation
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Antibody adviceTRAF2 antibody can be used for the detection of TRAF2 by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL.
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Suspention pH azideTRAF2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atTRAF2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr55959980
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Ncbi nrCAI15106
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr7186
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GENE symbolTRAF2
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Antigene nameTNF receptor-associated factor 2
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SourceHomo sapiens
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Protein nrQ12933
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTRAF2, TANK
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Short nameanti-TRAF2 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTRAF2 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetTNF receptor-associated factor 2, MGC:45012 and TRAP and TRAP3, TRAF2 and IDBG-92817 and ENSG00000127191 and 7186, metal ion binding, Plasma membranes, Traf2 and IDBG-146254 and ENSMUSG00000026942 and 22030, TRAF2 and IDBG-641438 and ENSBTAG00000010497 and 512355
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor associated factor 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-04-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- TNF receptor associated factors
- MicroRNA protein coding host genes
- Ring finger proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTRAF family member associated NFKB activator
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Synonyms gene
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Synonyms gene name
- TRAF family member-associated NFKB activator
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data