anti-TRAF2 Antibody

  • Catalog number
    3661
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    TRAF2 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a TNF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-kB activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.
  • Gene names
    TRAF2 Antibody: TRAP, TRAP3, MGC:45012, TNF receptor-associated factor 2, E3 ubiquitin-protein ligase TRAF2
  • Antibodie s label
    unlabelled serum
  • Purity
    TRAF2 Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    TRAF2 antibody was made against a 17 amino acid synthetic peptide from near the carboxy terminus of human TRAF2.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry, immuno precipitation
  • Antibody advice
    TRAF2 antibody can be used for the detection of TRAF2 by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL.
  • Suspention pH azide
    TRAF2 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    TRAF2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    55959980
  • Ncbi nr
    CAI15106
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    7186
  • GENE symbol
    TRAF2
  • Antigene name
    TNF receptor-associated factor 2
  • Source
    Homo sapiens
  • Protein nr
    Q12933
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    TRAF2  
  • Gene symbol
    TRAF2, TANK
  • Short name
    anti-TRAF2 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toTRAF2 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    TNF receptor-associated factor 2, MGC:45012 and TRAP and TRAP3, TRAF2 and IDBG-92817 and ENSG00000127191 and 7186, metal ion binding, Plasma membranes, Traf2 and IDBG-146254 and ENSMUSG00000026942 and 22030, TRAF2 and IDBG-641438 and ENSBTAG00000010497 and 512355
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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