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K858 for cell activation

K858 for cell activation is available 2 times from Biovision labs

B1073-50 | K858 for cell activation size: 50 mg | 706.07 USD

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B1073-10 | K858 for cell activation size: 10 mg | 220.09 USD

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Description K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC₅₀ = 1.3 µM) and an antitumor agent. Induces cell death in cancer cells, blocks centrosome separation, activates the spindle checkpoint, and induces mitotic arrest in cells accompanied by the formation of monopolar spindles.
Peptide sequence N/A
CAS number 72926-24-0
Molecular weight 277.34
Category BioChemicals
Other name N-(4-acetyl-5-methyl-5-phenyl-4,5-dihydro-1,3,4-thiadiazol-2-yl)acetamide
Molecular formula C₁₃H₁₅N₃O₂S
Physical appearance White to off-white solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions DMSO (>20 mg/ml)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and light
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetK858 for activation
Short name K858 for activation
Technique activation
Alternative name K858 to measure cellular activation
Tissue cell
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