Active Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)
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Catalog number
APA139Hu01
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Price
Please ask
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Size
1mg
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Source
NA
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Predicted Molecular Mass KD
19.6kDa
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Accurate Molecular Mass KD
19kDa
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Organism species
Homo sapiens (Human)
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Item Name
Tumor Necrosis Factor Related Apoptosis Inducing Ligand
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Alternative Names
CD253; TNFSF10; APO2L; Apo2-L; TL2; TRAIL; Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand
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Research Area
Apoptosis;Tumor immunity;
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Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
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Traits
Liquid
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Isoelectric Point
8.6
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Purity
> 95%
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Protein length
Val114~Gly281
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Tag
N-terminal His Tag
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Expression System
NA
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Application
Cell culture; Activity Assays.
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Description
This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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Gene target
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Gene symbol
TNFSF10, TNFRSF10B
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Short name
Active Tumor Necrosis Factor Apoptosis Ligand (TRAIL)
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Technique
apoptosis, apoptosis pathway
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Host
NA
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Species
Homo sapiens (Human)
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Alternative name
functionnal Tumor Necrosis Factor Related programmed cellular destruction Inducing Ligand (TRAIL)
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Alternative technique
celldeath
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Tissue
tumor
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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