anti- PTPN11 antibody
-
Catalog numberFNab06932
-
PricePlease ask
-
Size2X100μg
-
-
Formliquid
-
PurificationImmunogen affinity purified
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
BackgroundThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
-
Immunogenprotein tyrosine phosphatase, non-receptor type 11
-
SynonymsPTP2C, SHPTP2
-
Calculated MW71KDa
-
Uniprot IDQ06124
-
SpecificityHuman, Mouse, Rat
-
Tested ApplicationELISA, WB, IHC
-
Recommended dilutionWB: 1:500 - 1:1000; IHC: 1:50 - 1:100
-
Image1Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab06932( PTPN11 Antibody) at dilution of 1:50
-
Image4HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06932( PTPN11 Antibody) at dilution of 1:1000
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolPTPN11
-
Short nameanti- PTPN11 antibody
-
TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
-
HostRabbit
-
IsotypeIgG
-
Alternative nameantibody to- PTPN11 (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameprotein tyrosine phosphatase non-receptor type 11
-
Synonyms gene
-
Synonyms gene name
- Noonan syndrome 1
- protein tyrosine phosphatase, non-receptor type 11
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1993-03-03
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Protein tyrosine phosphatases non-receptor type
- SH2 domain containing
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data