CD32 Polyclonal Antibody

• Catalog number
  A1079-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  FCGR2B
• Target Alternative Name
  FCGR2B; CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthesized peptide derived from the C-terminal region of human CD32
• Accession
  P31994
• Gene Id
  2213
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Purification
  Synthesized peptide derived from the C-terminal region of human CD32
• Application
  WB, ELISA
• Positive Control
  WB: Hela cell lysate, Raji cell lysate
• Application And Usages
  Western Blot: 1:500 – 1:2000 ELISA: 1:20000
• Description
  Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  CD32  
• Gene symbol
  FCGR2B, FCGR2A
• Short name
  CD32 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Rabbit IgG
• Alternative name
  CD32 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:3618
• Gene
  FCGR2B
• Long gene name
  Fc gamma receptor IIb
• Synonyms gene
  • FCG2
  • FCGR2
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIb, receptor for (CD32)
  • Fc fragment of IgG, low affinity IIb, receptor (CD32)
  • Fc fragment of IgG receptor IIb
• Synonyms
  • CD32
  • CD32B
  • FcgammaRIIb
  • FcGRIIB
• GenBank acession
  • BC031992
• Locus
  1q23.3
• Discovery year
  1991-08-21
• Entrez gene record
  2213
• Pubmed identfication
  • 2139735
  • 19309690
• RefSeq identity
  • NM_004001
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000034470

Gene info

• Identity
  HGNC:3616
• Gene
  FCGR2A
• Long gene name
  Fc gamma receptor IIa
• Synonyms gene
  • FCG2
  • FCGR2A1
  • FCGR2
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG receptor IIa
• Synonyms
  • CD32
  • CD32A
  • IGFR2
  • CDw32
  • Fc-gamma-RIIa
  • FcgammaRIIa
• Synonyms name
  • Immunoglobulin G Fc receptor II
• GenBank acession
  • J03619
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2212
• Pubmed identfication
  • 2139735
  • 8994865
• RefSeq identity
  • NM_021642
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034469
• Locus Specific Databases
  • LRG_1109

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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