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Monoamine Oxidase MAO Fluorometric Kit

Monoamine Oxidase MAO Fluorometric Kit is available 3 times from Biovision labs

K796-100 | Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric) size: 100 assays | 680.87 USD

Catalog number K796-100
Supplier Biovision
Price 680.87 USD
Size 100 assays
Kit's description Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity, and tissue localization. MAO-A can oxidize primary amines such as serotonin and norepinephrine. MAO-A is a mitochondrial-bound enzyme that is ubiquitously expressed throughout the brain and other tissues. It has been implicated in panic, anxiety, and depression. Several MAO-A specific inhibitors such as clorgyline, brofaromine, toloxatone, tetrindole, etc. have been used as antidepressants, but their usage has been limited due to side effects. BioVision’s MAO-A Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-A inhibitors. The assay is based on the fluorometric detection of H2O2, one of the byproducts generated during the oxidative deamination of MAO substrate.
Highlights • Detection method: Fluorescence (Ex/Em = 535/587 nm) • Application: Screening/studying/characterizing MAO:A inhibitors
Kit's benefits • Rapid & sensitive • High-throughput assay to screen/study/characterize potential inhibitors of monoamine oxidase A • Includes Inhibitor Control [Clorgyline]
Category Monoamine oxidase A, MAO-A, MAO A
Contents • MAO-A Assay Buffer • OxiRedTM Probe (in DMSO) • MAO-A Enzyme (Lyophilized) • MAO-A Substrate (Lyophilized) • Developer (Lyophilized) • Inhibitor Control (Clorgyline) (Lyophilized)
Applications Screening/studying/characterizing MAO-A inhibitors
Description Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Gene targetMonoamine Oxidase MAO-A Inhibitor Screening Kit Fluorometric
Short name Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric)
Alternative name Monoamine Oxidase A (MAO-A) suppressor quantification reagent (fluorescence)
Alternative technique kits
1. Gene info
Identity 5661
Gene IGHV5-10-1
Long gene name immunoglobulin heavy variable 5-10-1
Synonyms gene
  • IGHV5-A
Synonyms gene name
  • immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
  • immunoglobulin heavy variable 5-A (provisional)
Synonyms
  • IGHV5-a
GenBank acession
  • X92227
Locus 14q32.33
Discovery year 2000-04-04
Entrez gene record 28386
RefSeq identity
  • NG_001019
Classification
  • Immunoglobulin heavy locus at 14q32.33
Havana BLAST/BLAT OTTHUMG00000191143
2. Gene info
Identity 6833
Gene MAOA
Long gene name monoamine oxidase A
Locus Xp11.3
Discovery year 1986-01-01
Entrez gene record 4128
RefSeq identity
  • NM_000240
Havana BLAST/BLAT OTTHUMG00000021387
Locus Specific Databases
  • Global Variome shared LOVD
Product images
    #0#.jpegMonoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric)

K795-100 | Monoamine Oxidase Activity (Total MAO/MAO-A/MAO-B) Fluorometric Assay Kit size: 100 assays | 583.44 USD

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K797-100 | Monoamine Oxidase B (MAO-B) Inhibitor Screening Kit (Fluorometric) size: 100 assays | 680.87 USD

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Kit's other name none
Storage condition -20°C
Shipping condition gel pack
Maximum time can be stored 12 months
Species reactivity see datasheet
Storage Conditions -20°C
Tag Line NA
Shipping Conditions gel pack
Shelf life 12 months
Species Reactivity NA
Sample Type • Biological fluids: Serum, plasma • Animal tissues: Brain, heart, liver, kidney, lung, cell lines (i.e. fibroblasts) etc.
Technique Assay
Host Assay
Alternative to gene target v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
Tissue total
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Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorom
Filters
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • Monoamine
  • Oxidase
  • MAO-A
  • Inhibitor
  • Screening
  • Kit
  • Fluorometric
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