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Long name
Mouse Monoclonal Antibody against Human CD17 / Lactosylceramide, Clone: MEM-68
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Antigen
CD17
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Species reactivity
Human (Homo sapiens)
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Negative species reactivity
at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
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Clonality
Monoclonal Antibody (Mab)
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Clone
MEM-68
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Applications
FC
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Immunogen
Pre-B cell line NALM-6
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Format conjugation
purified; unconjugated
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Specificity
The mouse monoclonal antibody MEM-68 recognizes CD17, a membrane lipid moiety lactosylceramide expressed on granulocytes, monocytes and platelets._x000D_
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Research area
CD and Related Antigens (Human)
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Concentration
1 mg/ml
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Storage buffer
Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
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Shipping and storage
Mouse Monoclonal Antibody against Human CD17 / Lactosylceramide, Clone: MEM-68 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
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Background
CD17, lactosylceramide, is an ubiquitous glycosphingolipid with uncharged disaccharide headgroup, highly enriched in lipid raft-derived structures. Besides playing a pivotal role in the biosynthesis of complex glycosphingilipids, lactosylceramide is involved in cell-cell and cell-matrix interactions and in signaling events linked to cell differentiation, development, apoptosis and oncogenesis. Lactosylceramide regulates integrin functions and production of nitric oxide. Its expression defines successive stages in the maturation of myeloid cells.
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Purity
> 95% (by SDS-PAGE)
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Purification method
Purified by precipitation and chromatography
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References
Contact us for the most recent list of references
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Properties
If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps