Inauhzin

• Catalog number
  9555-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2-((5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-1-(10H-phenothiazin-10-yl)butan-1-one
• Description
  Inauhzin is a potent SIRT inhibitor that effectively reactivates p53 by inhibiting SIRT1 activity. Inauhzin inhibits cell proliferation, induces senescence, and p53-dependent apoptosis of human cancer cells without apparent toxicity to normal cells.
• CAS Number
  309271-94-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₁₉N₅OS₂
• Molecular Weight
  469.58
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent SIRT inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  5494506
• PubChem CID Link
• SMILES
  CCC(C(=O)N1C2=CC=CC=C2SC3=CC=CC=C31)SC4=NC5=C(C6=CC=CC=C6N5)N=N4
• InChi
  InChI=1S/C25H19N5OS2/c1-2-19(33-25-27-23-22(28-29-25)15-9-3-4-10-16(15)26-23)24(31)30-17-11-5-7-13-20(17)32-21-14-8-6-12-18(21)30/h3-14,19H,2H2,1H3,(H,26,27,29)
• InChi Key
  VHUOXERIKQWIJE-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Inauhzin  
• Short name
  Inauhzin
• Alternative name
  Inauhzin

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