TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA)
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Catalog numberMBS631996
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PricePlease ask
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Size5x0.5 mg
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Products_typeAntibody
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Products_short_name[TCR, alpha, beta]
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Products_name_syn[Anti -TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA)]
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Other_names[TCR, partial]
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ClonalityMonoclonal
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Clone[H57-597]
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ReactivityMouse
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SpecificityRecognizes the common epitope of the beta chain of the mouse alpha/beta T cell receptor (TCR) complex. Does not react with gamma/delta TCR-bearing cells.
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PurityPurified Purified
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FormSupplied as a liquid in 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_applicationImmunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionThe TCR, alpha, beta (T Receptor, T- Receptor beta-1 Chain C Region, TRBC1, T- Receptor alpha Chain C Region, TRAC, TCRA) is a α- or alpha protein sometimes glycoprotein present in blood. For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolTRAC, TRA, TRBC1, NCOR2
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Short nameTCR, alpha, beta (T Receptor, T- Receptor beta-1 Chain C Region, TRBC1, T- Receptor alpha Chain C Region, TRAC, TCRA)
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HostHamster
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IsotypeIgG
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Alternative nameTCR, a, b (T cellular Receptor, T-cellular Receptor b-1 epitope C Region, TRBC1, T-cellular Receptor a epitope C Region, TRAC, TCRA)
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Tissuecell, region
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Gene info
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Identity
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Gene
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Long gene nameT cell receptor alpha constant
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- T cell receptor alpha locus at 14q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameT cell receptor alpha locus
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Synonyms gene
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Synonyms gene name
- TCRA, TRA@
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- T cell receptor alpha locus at 14q11.2
Gene info
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Identity
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Gene
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Long gene nameT cell receptor beta constant 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-05-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- T cell receptor beta locus at 7q34
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear receptor corepressor 2
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Synonyms gene name
- nuclear receptor co-repressor 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myb/SANT domain containing
- NCoR/SMRT transcriptional repression complex subunits
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VEGA ID