DNA Ligase IV/LIG4 Antibody, ALEXA FLUOR 488

  • Catalog number
    bs-1677R-A488
  • Price
    Please ask
  • Size
    100ul
  • Long name
    DNA Ligase IV/LIG4 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
  • Also known as
    Anti-DNA Ligase IV/LIG4 PAb ALEXA FLUOR 488
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 488
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    DNA Ligase IV/LIG4
  • Specificity
    This is a highly specific antibody against DNA Ligase IV/LIG4.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    60-110/911
  • Subcellular location
    Nucleus
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Ligase IV
  • Gene ID Number
    3981
  • Swiss Prot
    P49917
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    499nm/519nm
  • Synonyms
    LIG4S; DNA ligase 4; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4; LIG4
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-DNA Ligase IV/LIG4 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor
  • French translation
    anticorps
  • Gene target
    DNA   Ligase   IV/LIG4  
  • Gene symbol
    LIG4, PRKDC, HLA-DOA
  • Short name
    Anti-DNA Ligase IV/LIG4
  • Technique
    Antibody, dna, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 488
  • Alternative name
    DNA Ligase IV/LIG4 Polyclonal Antibody, ALEXA FLUOR 488
  • Alternative technique
    antibodies
  • Alternative to gene target
    ligase IV, DNA, ATP-dependent, LIG4S, LIG4 and IDBG-49744 and ENSG00000174405 and 3981, metal ion binding, nuclei, Lig4 and IDBG-131943 and ENSMUSG00000049717 and 319583, LIG4 and IDBG-633610 and ENSBTAG00000015868 and 781252
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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