anti- CD3 delta antibody
-
Catalog numberFNab01456
-
PricePlease ask
-
Size2X100μg
-
-
Formliquid
-
PurificationImmunogen affinity purified
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
BackgroundThe protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
-
ImmunogenCD3d molecule, delta (CD3-TCR complex)
-
Calculated MW19 kDa
-
SpecificityHuman, Rat
-
Tested ApplicationELISA, WB, IHC
-
Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200
-
Image1Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01456( CD3D Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
-
Image4Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01456(CD3D antibody) at dilution of 1:1000
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCD3D
-
Short nameanti- CD3 delta antibody
-
TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
-
HostRabbit
-
IsotypeIgG
-
Alternative nameantibody to- CD3 delta (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameCD3d molecule
-
Synonyms gene
-
Synonyms gene name
- CD3d antigen, delta polypeptide (TiT3 complex)
- CD3d molecule, delta (CD3-TCR complex)
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
RefSeq identity
-
Classification
- CD molecules
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data