NOX2/gp91phox Antibody, ALEXA FLUOR 555

• Catalog number
  bs-3889R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  NOX2/gp91phox Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-NOX2/gp91phox PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  NOX2/gp91phox
• Specificity
  This is a highly specific antibody against NOX2/gp91phox.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  490-540/570
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NOX2/gp91phox
• Gene ID Number
  1536
• Swiss Prot
  P04839
• Tested applications
  IF(IHC-P), IF(ICC)
• Recommended dilutions
  IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  CGD; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; p22 phagocyte B-cytochrome; CYBB
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  NOX2/gp91phox  
• Gene symbol
  CYBB
• Short name
  Anti-NOX2/gp91phox
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  NOX2/gp91phox Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2578
• Gene
  CYBB
• Long gene name
  cytochrome b-245 beta chain
• Synonyms gene
  • CGD
• Synonyms gene name
  • chronic granulomatous disease
  • cytochrome b-245, beta polypeptide
• Synonyms
  • GP91-PHOX
  • NOX2
• Synonyms name
  • NADPH oxidase 2
• GenBank acession
  • X04011
• Locus
  Xp21.1-p11.4
• Discovery year
  1986-01-01
• Entrez gene record
  1536
• VEGA ID
  OTTHUMG00000033175
• Locus Specific Databases
  • CYBBbase: Mutation registry for X-linked chronic granulomatous disease (previously known as X-CDGbase)
  • LRG_53

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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