MLCK Antibody, Cy5.5 Conjugated

• Catalog number
  bs-4705R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  MLCK Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MLCK
• Specificity
  This is a highly specific antibody against MLCK.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  700-750/1914
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from human MLCK
• Gene ID number
  4638
• Swiss Prot
  Q15746
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  KRP; AAT7; MLCK; MLCK1; MYLK1; smMLCK; MLCK108; MLCK210; MSTP083; Myosin light chain kinase, smooth muscle; Kinase-related protein; Telokin; MYLK
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  MLCK   Conjugated  
• Gene symbol
  MYLK3, MYLK
• Short name
  Anti-MLCK
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-MLCK PAb Cy5.5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29826
• Gene
  MYLK3
• Long gene name
  myosin light chain kinase 3
• Synonyms
  • caMLCK
  • MLCK
• Synonyms name
  • MLC kinase
• GenBank acession
  • AJ247087
• Locus
  16q11.2
• Discovery year
  2008-01-23
• Entrez gene record
  91807
• Pubmed identfication
  • 17885681
• RefSeq identity
  • NM_182493
• Classification
  • Myosin light chain kinase family
• VEGA ID
  OTTHUMG00000132543

Gene info

• Identity
  HGNC:7590
• Gene
  MYLK
• Long gene name
  myosin light chain kinase
• Synonyms gene name
  • myosin, light polypeptide kinase
• Synonyms
  • MLCK
  • smMLCK
  • MYLK1
  • MLCK1
• Synonyms name
  • smooth muscle myosin light chain kinase
• GenBank acession
  • X85337
• Locus
  3q21.1
• Discovery year
  1995-07-14
• Entrez gene record
  4638
• Pubmed identfication
  • 8575746
• RefSeq identity
  • NM_053025
• Classification
  • Fibronectin type III domain containing
  • Myosin light chain kinase family
  • I-set domain containing
• VEGA ID
  OTTHUMG00000141304

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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