3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide
Cell-permeable. A reversible, noncompetitive inhibitor of dynamin that interferes in vitro with the GTPase activity of dynamin1, dynamin2, and Drp1, the mitochondrial dynamin, but not of other small GTPases. Dynasore acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation within seconds of dynasore addition.
C₁₈H₁₄N₂O₄ . H₂O
Is it cell-permeable?
≥98% by NMR
Is this a salt?
Protect from air and light
Maximum time for storage
DMSO (10 mg/ml) or EtOH (1 mg/ml)
For cells, cell lines and tissues in culture till half confluency.