anti-CLDN11 Antibody

• Catalog number
  27-908
• Price
  Please ask
• Size
  50 ug

• Gene info
  CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
• Gene names
  CLDN11, OSP, OTM
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN11.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  CLDN11 antibody can be used for detection of CLDN11 by ELISA at 1:312500. CLDN11 antibody can be used for detection of CLDN11 by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store CLDN11 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Dog
• Omim nr
  10938016
• Ncbi nr
  NP_005593
• KDa
  22 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  5010
• GENE symbol
  CLDN11
• Antigene name
  claudin 11
• Source
  Homo sapiens
• Protein nr
  O75508
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CLDN11  
• Gene symbol
  CLDN11
• Short name
  anti-CLDN11 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toclaudin 11 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  claudin 11, OSP and OTM, CLDN11 and IDBG-64549 and ENSG00000013297 and 5010, identical protein binding, Cell surfaces, Cldn11 and IDBG-136362 and ENSMUSG00000037625 and 18417, BT.71689 and IDBG-636448 and ENSBTAG00000019060 and 508268

Gene info

• Identity
  HGNC:8514
• Gene
  CLDN11
• Long gene name
  claudin 11
• Synonyms gene
  • OTM
• Synonyms gene name
  • oligodendrocyte transmembrane protein
• Synonyms
  • OSP
• GenBank acession
  • AF068863
• Locus
  3q26.2
• Discovery year
  1996-09-13
• Entrez gene record
  5010
• Pubmed identfication
  • 8661061
  • 8797478
• RefSeq identity
  • NM_005602
• Classification
  • MicroRNA protein coding host genes
  • Claudins
• VEGA ID
  OTTHUMG00000158940

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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