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Altiratinib for cell activation

Altiratinib for cell activation is available 2 times from Biovision labs

9563-5 | Altiratinib for cell activation size: 5 mg | 212.51 USD

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9563-25 | Altiratinib for cell activation size: 25 mg | 671.79 USD

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Other name N-(4-((2-(cyclopropanecarboxamido)pyridin-4-yl)oxy)-2,5-difluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide; DCC-2701
Supplied with N/A
Description Altiratinib is a selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. It effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Through its balanced inhibitory potency versus MET, TIE2, and VEGFR2, altiratinib inhibits three major evasive (re)vascularization and resistance pathways (HGF, ANG, and VEGF) and blocks tumor invasion and metastasis. Displays blood-brain barrier penetration.
Category Biochemicals
Molecular formula C₂₆H₂₁F₃N₄O₄
Is it cell-permeable? Yes
Molecular weight 510.46
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 1345847-93-9
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance White to off-white solid
Reconstitute instructions DMSO (>30 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name Altiratinib for activation
Technique activation
Alternative name Altiratinib to measure cellular activation
Tissue cell
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